Lewis Thomas

Scientist

1913-11-25

Quotes by Lewis Thomas

Worrying is the most natural and spontaneous of all human functions. It is time to acknowledge this, perhaps even to learn to do it better.
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Statistically, the probability of any one of us being here is so small that you'd think the mere fact of existing would keep us all in a contented dazzlement of surprise. We are alive against the stupendous odds of genetics, infinitely outnumbered by all the alternates who might, except for luck, be in our places.Even more astounding is our statistical improbability in physical terms. The normal, predictable state of matter throughout the universe is randomness, a relaxed sort of equilibrium, with atoms and their particles scattered around in an amorphous muddle. We, in brilliant contrast, are completely organized structures, squirming with information at every covalent bond. We make our living by catching electrons at the moment of their excitement by solar photons, swiping the energy released at the instant of each jump and storing it up in intricate loops fro ourselves. We violate probability, by our nature. To be able to do this systematically, and in such wild varieties of form, from viruses to whales, is extremely unlikely; to have sustained the effort successfully for the several billion years of our existence, without drifting back into randomness, was nearly a mathematical impossibility. Add to this the biological improbability that makes each member of our own species unique. Everyone is one in 3 billion at the moment, which describes the odds. Each of us is a self-contained, free-standing individual, labeled by specific protein configurations at the surfaces of cells, identifiable by whorls of fingertip skin, maybe even by special medleys of fragrance. You'd think we'd never stop dancing.
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Working on a typewriter by touch, like riding a bicycle or strolling on a path, is best done by not giving it a glancing thought. Once you do, your fingers fumble and hit the wrong keys. To do things involving practiced skills, you need to turn loose the systems of muscles and nerves responsible for each maneuver, place them on their own, and stay out of it. There is no real loss of authority in this, since you get to decide whether to do the thing or not, and you can intervene and embellish the technique any time you like; if you want to ride a bicycle backward, or walk with an eccentric loping gait giving a little skip every fourth step, whistling at the same time, you can do that. But if you concentrate your attention on the details, keeping in touch with each muscle, thrusting yourself into a free fall with each step and catching yourself at the last moment by sticking out the other foot in time to break the fall, you will end up immobilized, vibrating with fatigue. It is a blessing to have options for choice and change in the learning of such unconsciously coordinated acts. If we were born with all these knacks inbuilt, automated like ants, we would surely miss the variety. It would be a less interesting world if we all walked and skipped alike, and never fell from bicycles. If we were all genetically programmed to play the piano deftly from birth, we might never learn to understand music.
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The individual parts played by other instrumentalists-- crickets or earthworms, for instance-- may not have the sound of music by themselves, but we hear them out of context. If we could listen to them all at once, fully orchestrated, in their immense ensemble, we might become aware of the counterpoint, the balance of tones and timbres and harmonics, the sonorities. The recorded songs of the humpback whale, filled with tensions and resolutions, ambiguities and allusions, incomplete, can be listened to as a a part of music, like an isolated section of an orchestra. If we had better hearing, we could discern the descants of sea birds, the rhythmic tympani of schools of mollusks, or even the distant harmonies of midges hanging over meadows in the sun, the combined sound might lift us off our feet.
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It is not a simple thing to decide where we fit, for at one time or another in our lives we manage to organize in every imaginable social arrangement...We have names to label each as self, and we believe without reservation that this system of taxonomy will guarantee the entity, the absolute separateness in each of us, but the mechanism has no discernible function in the center of a crowded city; we are essentially nameless, most of our time.
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It is in our collective behavior that we are the most mysterious. We won't be able to construct machines like ourselves until we've understood this, and we're not even close. All we know is the phenomenon: we spend our time sending messages to each other, talking and trying to listen at the same time, exchanging information. This seems to be our most urgent biological function; it is what we do with our lives. By the time we reach the end, each of us has taken in a staggering store, enough to exhaust any computer, much of it incomprehensible, and we generally manage to put out even more than we take in. Information is our source of energy; we are driven by it. It has become a tremendous enterprise, a kind of energy system on its own. All 3 billion of us are being connected by telephones, radios, television sets, airplanes, satellites, harangues on public-address systems, newspapers, magazines, leaflets dropped from great heights, words got in edgewise. We are becoming a grid, a circuitry around the earth.
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Not all social animals are social with the same degree of commitment. In some species, the members are so tied to each other and interdependent as to seem the loosely conjoined cells of a tissue. The social insects are like this; they move, and live all their lives, in a mass; a beehive is a spherical animal. In other species, less compulsively social, the members make their homes together, pool resources, travel in packs or schools, and share the food, but any single one can survive solitary, detached from the rest. Others are social only in the sense of being more or less congenial, meeting from time to time in committees, using social gatherings as ad hoc occasions for feeding and breeding. Some animals simply nod at each other in passing, never reaching even a first-name relationship.
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It is hard to feel affection for something as totally impersonal as the atmosphere, and yet there it is, as much a part and product of life as wine and bread. Taken all in al, the sky is a miraculous achievement. It works, and for what it is designed to accomplish it is as infallible as anything in nature. I doubt whether any of us could think of a way to improve on it, beyond maybe shifting a local cloud from here to there on occasion. The word 'chance' does not serve to account well for structures of such magnificence...We should credit it for what it is: for sheer size and perfection of function, it is far and away the grandest product of collaboration in all of nature.It breathes for us, and it does another thing for our pleasure. Each day, millions of meteorites fall against the outer limits of the membrane and are burned to nothing by the friction. Without this shelter, our surface would long since have become the pounded powder of the moon. Even though our receptors are not sensitive enough to hear it, there is comfort in knowing the sound is there overhead, like the random noise of rain on the roof at night.
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Perhaps it is in this respect that language differs most sharply from other biologic systems for communication. Ambiguity seems to be an essential, indispensable element for the transfer of information from one place to another by words, where matters of real importance are concerned. It is often necessary, for meaning to come through, that there be an almost vague sense of strangeness and askewness. Speechless animals and cells cannot do this. The specifically locked-on antigen at the surface of a lymphocyte does not send the cell off in search of something totally different; when a bee is tracking sugar by polarized light, observing the sun as though consulting his watch, he does not veer away to discover an unimaginable marvel of a flower. Only the human mind is designed to work in this way, programmed to drift away in the presence of locked-on information, straying from each point in a hunt for a better, different point.If it were not for the capacity for ambiguity, for the sensing of strangeness, the words in all languages provide, we would have no way of recognizing the layers of counterpoint in meaning, and we might be spending all our time sitting on stone fences, staring into the sun. To be sure, we would always have had some everyday use to make of the alphabet, and we might have reached the same capacity for small talk, but it is unlikely that we would have been able to evolve from words to Bach. The great thing about human language is that it prevents us from sticking to the matter at hand.
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However, I have a stronger hunch that the greatest part of the important biomedical research waiting to be done is in the class of basic science. There is an abundance of interesting fact relating to all our major diseases, and more items of information are coming in steadily from all quarters in biology. The new mass of knowledge is still formless, in complete, lacking the essential threads of connection, displaying misleading signals at every turn, riddled with blind alleys. There are fascinating ideas all over the place, irresistible experiments beyond numbering, all sorts of new ways into the maze of problems. But every next move is unpredictable, every outcome uncertain. It is a puzzling time, but a very good time. I do not know how you lay out orderly plans for this kind of activity, but I suppose you could find out by looking through the disorderly records of the past hundred years. Somehow, the atmosphere has to be set so that a disquieting sense of being wrong is the normal attitude of the investigators. It has to be taken for granted that the only way in is by riding the unencumbered human imagination, with the special rigor required for recognizing that something can be highly improbable, maybe almost impossible, and at the same time true.Locally, a good way to tell how the work is going is to listen in the corridors. If you hear the word, Impossible! spoken as an expletive, followed by laughter, you will know that someone's orderly research plan is coming along nicely.
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The capacity to blunder slightly is the real marvel of DNA. Without this special attribute, we would still be anaerobic bacteria and there would be no music.
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The greatest single achievement of nature to date was surely the invention of the molecule DNA.
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I am a member of a fragile species, still new to the earth, the youngest creatures of any scale, here only a few moments as evolutionary time is measured, a juvenile species, a child of a species. We are only tentatively set in place, error prone, at risk of fumbling, in real danger at the moment of leaving behind only a thin layer of of our fossils, radioactive at that.
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Statistically, the probability of any one of us being here is so small that the mere fact of our existence should keep us all in a state of contented dazzlement.
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Statistically, the probability of any one of us being here is so small that you'd think the mere fact of existing would keep us all in a contented dazzlement of surprise. We are alive against the stupendous odds of genetics, infinitely outnumbered by all the alternates who might, except for luck, be in our places.Even more astounding is our statistical improbability in physical terms. The normal, predictable state of matter throughout the universe is randomness, a relaxed sort of equilibrium, with atoms and their particles scattered around in an amorphous muddle. We, in brilliant contrast, are completely organized structures, squirming with information at every covalent bond. We make our living by catching electrons at the moment of their excitement by solar photons, swiping the energy released at the instant of each jump and storing it up in intricate loops fro ourselves. We violate probability, by our nature. To be able to do this systematically, and in such wild varieties of form, from viruses to whales, is extremely unlikely; to have sustained the effort successfully for the several billion years of our existence, without drifting back into randomness, was nearly a mathematical impossibility. Add to this the biological improbability that makes each member of our own species unique. Everyone is one in 3 billion at the moment, which describes the odds. Each of us is a self-contained, free-standing individual, labeled by specific protein configurations at the surfaces of cells, identifiable by whorls of fingertip skin, maybe even by special medleys of fragrance. You'd think we'd never stop dancing.
Read quote
Perhaps it is in this respect that language differs most sharply from other biologic systems for communication. Ambiguity seems to be an essential, indispensable element for the transfer of information from one place to another by words, where matters of real importance are concerned. It is often necessary, for meaning to come through, that there be an almost vague sense of strangeness and askewness. Speechless animals and cells cannot do this. The specifically locked-on antigen at the surface of a lymphocyte does not send the cell off in search of something totally different; when a bee is tracking sugar by polarized light, observing the sun as though consulting his watch, he does not veer away to discover an unimaginable marvel of a flower. Only the human mind is designed to work in this way, programmed to drift away in the presence of locked-on information, straying from each point in a hunt for a better, different point.If it were not for the capacity for ambiguity, for the sensing of strangeness, the words in all languages provide, we would have no way of recognizing the layers of counterpoint in meaning, and we might be spending all our time sitting on stone fences, staring into the sun. To be sure, we would always have had some everyday use to make of the alphabet, and we might have reached the same capacity for small talk, but it is unlikely that we would have been able to evolve from words to Bach. The great thing about human language is that it prevents us from sticking to the matter at hand.
Read quote
Not all social animals are social with the same degree of commitment. In some species, the members are so tied to each other and interdependent as to seem the loosely conjoined cells of a tissue. The social insects are like this; they move, and live all their lives, in a mass; a beehive is a spherical animal. In other species, less compulsively social, the members make their homes together, pool resources, travel in packs or schools, and share the food, but any single one can survive solitary, detached from the rest. Others are social only in the sense of being more or less congenial, meeting from time to time in committees, using social gatherings as ad hoc occasions for feeding and breeding. Some animals simply nod at each other in passing, never reaching even a first-name relationship.
Read quote
Worrying is the most natural and spontaneous of all human functions. It is time to acknowledge this, perhaps even to learn to do it better.
Read quote
I am a member of a fragile species, still new to the earth, the youngest creatures of any scale, here only a few moments as evolutionary time is measured, a juvenile species, a child of a species. We are only tentatively set in place, error prone, at risk of fumbling, in real danger at the moment of leaving behind only a thin layer of of our fossils, radioactive at that.
Read quote
It is in our collective behavior that we are the most mysterious. We won't be able to construct machines like ourselves until we've understood this, and we're not even close. All we know is the phenomenon: we spend our time sending messages to each other, talking and trying to listen at the same time, exchanging information. This seems to be our most urgent biological function; it is what we do with our lives. By the time we reach the end, each of us has taken in a staggering store, enough to exhaust any computer, much of it incomprehensible, and we generally manage to put out even more than we take in. Information is our source of energy; we are driven by it. It has become a tremendous enterprise, a kind of energy system on its own. All 3 billion of us are being connected by telephones, radios, television sets, airplanes, satellites, harangues on public-address systems, newspapers, magazines, leaflets dropped from great heights, words got in edgewise. We are becoming a grid, a circuitry around the earth.
Read quote